ABSTRACT
Background: The ABO and Rhesus (Rh) blood group system are proved to be useful for blood transfusion purposes. They are also useful for organ transplantation, genetic research, and anthropology. The frequency and distribution of ABO and Rh blood group vary in different populations throughout the world. The knowledge of blood group distribution in respective city or region plays crucial role in the management of blood bank and transfusion services in those areas. Aim and Objectives: The present study was conducted to determine the frequency and distribution of ABO and Rh blood groups in blood donors of tertiary health care center. Materials and Methods: This study was conducted in tertiary care hospital-attached blood bank among the blood donors, who donated blood during the period from January 2017 to December 2021. ABO and Rh blood grouping of these donors were performed by tube agglutination method. Results: Out of 14,409 blood donors, 8,138 (56.5%) were male donors and 6,271 (43.5%) were female donors. The most frequent blood group was O (41.4%) and least common was AB (5.1%). The 95.7% blood donors were Rh positive and 4.3% were Rh negative. Conclusion: In the ABO blood group system, “O” blood group was most common and AB blood group was least common and in Rh blood group system, the Rh positive blood group was more common.